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Publications

Selected publications and presentations

Books / Book Chapters

  1. R. N. Dave and T. Sudkamp, Editors, 18th International Conference of the North American Fuzzy Information Processing Society --NAFIPS: Real World Applications of Fuzzy Logic and Soft Computing, IEEE Press, Piscataway, New Jersey, 1999. ISBN: 0-7803-5211-4

  2. L.-S. Fan and C. Zhu, Principles of Gas-Solid Flows, 557 pages, Cambridge University Press, 1998.

  3. Fu, T. and R. N. Davé, "Segmenting Curved Surfaces from Range Images," in Advances in Manufacturing Systems: Design, Modeling and Analysis, Eds. Sodhi, Zhou, and Das, Elsevier, Amsterdam, pp. 347-352, 1994.

  4. Chang, S-C. and R. N. Davé, "Identification of Nonlinear Dynamical Systems Using Fuzzy Neural Networks," in Advances in Manufacturing Systems: Design, Modeling and Analysis, Eds. Sodhi, Zhou, and Das, Elsevier, Amsterdam, pp. 457-462, 1994.


Journal Papers

  • M. Azad, J. Moreno, R. N. Davé, "Stable and Fast-Dissolving Amorphous Drug Composites Preparation via Impregnation of Neusilin® UFL2," Journal of Pharmaceutical Sciences, 107, 170-182, 2018.  

  • L. Chen, X. Ding, Z. He, Z. Huang, K. T. Kunnath, K. Zheng, R. N. Davé, "Surface engineered excipients: I. Improved functional properties of fine grade microcrystalline cellulose," International Journal of Pharmaceutics, 536(1), pp. 127-137, 2018. 

  • L. Zhang, Y. Li, M. Abed, R. N. Davé, "Incorporation of surface-modified dry micronized poorly water-soluble drug powders into polymer strip films," International Journal of Pharmaceutics, 535:462-472, 2018. 

  • M. Capece, R. N. Davé, E. Bilgili, "A Pseudo-coupled DEM-Non-linear PBM Approach for Simulating the Evolution of Particle Size during Dry Milling," Powder Technology, Volume 323, Pages 374-384, January 2018. 

  • A. Bhakay, E. Bilgili, R. N. Davé, "Quiescent and Agitated Redispersion as a Tool for Evaluating Dispersant Effectiveness in Dissolution Enhancement of Drug-Laden Nanocomposites," AAPS Pharmaceutical Science and Technology, 19(1), pp. 436-447, 2018. 

  • Z. Huang, W. Xiong, X. Deng, S. Bhaumik, R. N. Davé, "Improving blend content uniformity via dry particle coating of micronized drug powders", European Journal of Pharmaceutical Sciences, 104, 344-355, 15 June 2017. 

  • X. Deng, R. N. Davé, "Adhesion and friction of dry-coated nano-rough particles," Powder Technology, Special Issue: Modelling & Simulation, 314, pp. 20-27, 1 June 2017. 

  • Y. Ying, C. Beck, A. Wu, R. N. Davé, Z. Iqbal, "Polymorph formation in fenofibrate in the absence and presence of polymer stabilizers: A low frequency Raman and differential scanning calorimetry study," Journal of Raman Spectroscopy, 48(5), pp. 750-757, 2017. 

  • S. M. Krull, J. Moreno, M. Li, E. Bilgili, R. N. Davé, "Critical material attributes (CMAs) of strip films loaded with poorly water-soluble drug nanoparticles: III. Impact of drug nanoparticle loading", International Journal of Pharmaceutics, 523(1), pp. 33-41, 2017. 

  • X. Deng, R. N. Davé, "Properties of force networks in jammed granular media," Granular Matter, 19(2), 27, 2017. 

  • M. Capece, Z. Huang, R. Davé, “Insight into a Novel Strategy for the Design of Tablet Formulations Intended for Direct Compression”, Journal of Pharmaceutical Sciences, 106(6):1608-1617, 2017

  • X. Deng, R. N. Davé, “Breakage of fractal agglomerates”, Chemical Engineering Science, 161(6):117-126, 2017

  • S. M. Krull, J. Ammirata, S. Bawa, M. Li, E. Bilgili, R. Davé, “Critical material attributes (CMAs) of strip films loaded with poorly water-soluble drug nanoparticles: II. Impact of polymer molecular weight”, Journal of Pharmaceutical Sciences, 106(2):619-628, 2017

  • M. Azad, J. Moreno, E. Bilgili, R. Davé, “Fast Dissolution of Poorly Water Soluble Drugs from Fluidized Bed Coated Nanocomposites: Impact of Carrier Size”, International Journal of Pharmaceutics, 513(1-2):319-331, 2016

 

Patents and Applications

  • Method of Particle Coating, US patent # US6197369, Issued March 6, 2001. (filed: Sept. 30, 1999) (Inventors: S. Watano, R. Pfeffer, R. Dave)

  • Method and Apparatus for Magnetically Mediated Controlled Powder Discharge, US patent # 6,471,096, Issued October 29, 2002, (filed on 09/27/1999) (Inventor: R. Dave)

  • Polymer Coating/Encapsulation of Nanoparticles Using a  Supercritical Antisolvent Process, US Patent Issued, #  US 7,537,803 B2, May 26, 2009. (Inventors: Yulu Wang, R. Pfeffer, R. Dave)

  • System and Method for Nanoparticle and Nanoagglomerate Fluidization, Full US and International Patent Application, # 10/900,868, filed Fall 2004, issued Feb 9, 2010, US 7,658,340 B2. (Inventors: R. Pfeffer, C. Nam, R. Dave, Q. Liu, J. Quevedo, Q. Yu)

  • Fractal Structured Nanoagglomerates as Filter Media, Provisional Patent Application, # 60/676,758, filed, 05/02/05, non-provisional filed, 05/02/2006. Patent issued, U. S. Patent # 7,645,327 on January 12, 2010.

  • Net Shaping Manufacturing Processes and Compositions, PCT - Patent Cooperation Treaty, # PCT/US2004/036528, filed 11/02/04, US Patent 8,163,114, issued on 4/24/2012 (Inventors: Costas G. Gogos, Robert Pfeffer, Theodore Davidson, Rajesh N. Dave, Ming-Wan Young, Banian Qian)

  • Continuous High Speed Coating of Finely Ground Particles, Filing Date: 07/14/2006, App No: 11/457501, filed by US ARMY (Inventors: Ming-Wan Young, Costas George Gogos, Jun Yang, Rajesh Dave, Linjie Zhu, Peter Bonnett, William Schepige) US Patent # 8,252,370, issued on August 28, 2012.

  • Taste masked active pharmaceutical powder compositions and processes for making them, US Patent 9,993,041 B2 and foreign counter-parts, issued March 31, 2015. (Inventors: D. To, R. N. Davé)

  • Solventless Mixing Process for Coating Pharmaceutical Ingredients, U.S. Patent no. 9,107,851 and foreign counterparts, issued August 18, 2015. (Inventors: Rajesh N. Dave, Maxx W. Capece, Daniel To) (US Patent Application # 13/651,977 Filed 10/15/2012)

  • Systems and Methods for Superdisintegrant-Based Composite Particles for Dispersion and Dissolution of Agents, US Patent No. 9,452,107, issued September 27, 2016. (US Patent Application # 13/829,948, filed March 13, 2013) (Inventors: E. Bilgili, A. Bhakay, M. Azad, R. N. Davé

  • Powder Fluidization Apparatus, Japanese patent application, filed, 2000. (Inventors: S. Watano, R. Pfeffer, R. Dave)

  • Aerated Vibrofluidization and Aerated Magnetically Assisted Fluidization of Nanoparticles, Serial No. 60/490,912, filed July 29, 2003 (The provisional patent application was converted to a Full Regular Application) (Inventors: C. Nam, R. Pfeffer, R. Dave)

  • Nanoparticle Coating or Encapsulation Using Supercritical Antisolvent Process (SAS), Serial No. 60/461,506, filed April 8, 2003. (The provisional patent application is now converted to a Full Regular Application) (Inventors: Yulu Wang, R. Pfeffer, R. Dave)

  • Concentric Nozzle with Ultrasonic Agitation, PPA Filed to USPTO, Application No. 60/545,584 filed February 19, 2004 (Inventors: J-J. Luo, R. Dave, R. Pfeffer)

  • Net Shape Manufacturing Processes and Compositions, Application No. 10/819,898, filed April 7, 2004, (Inventors: B. Qian, C. Gogos, M. Young, R. Dave, R. Pfeffer, etal)

  • Ultraviolet Particle Coating Processes, Application No. 60/557,479, filed March 30, 2004. (Inventors: Ming-Wan Young, Bainian Qian, Costas Gogos, Rajesh Dave)

  • Ordered Particle Structures and Methods of Making Same, filed June 28, 2004. (Inventors: B. Qian, C. Gogos, M. Young, R. Dave, R. Pfeffer, etal)

  • Net Shaping Manufacturing Processes and Compositions, PCT - Patent Cooperation Treaty, # PCT/US2004/036528,  filed 11/02/04, (Inventors: Costas G. Gogos, Rajesh N. Dave, Robert Pfeffer)

  • Ultraviolet Particle Coating Systems and Processes, Full US Patent Application, # 11/094,842, filed 03/30/05. (Inventors: Costas G. Gogos, Rajesh N. Dave, Ming Wan Young, Banian Qian)

  • System and Method for Nanoparticle and Nanoagglomerate Fluidization, Full US and International Patent Application, # 10/900,868,  filed Fall 2004. (Inventors: R. Pfeffer, R. Dave, C. Nam, Q. Liu, J. Quevedo, Q. Yu)

  • Fractal Structured Nanoagglomerates as Filter Media, Provisional Patent Application, # 60/676,758, filed, 05/02/05. (Inventors: R. Pfeffer, R. Dave, S. Dukhin, J. Quevedo, Q. Yu)

  • Dry Particle Coating of Cohesive Powders and Associated Methods, Provisional Patent Application filed, August 31, 2005. (Inventors: R. Dave, R. Pfeffer, J. Yang, Y. Chen)

  • Method for Manufacturing Fine and Nano Particles and Coating Thereof, Provisional Patent Application filed, November 8, 2005. (Inventors: B. Khusid, A. Gokhale, R. N. Dave, R. Pfeffer)

  • Dry coating and downstream processing of cohesive powders, Patent Application # 20070053846, filed, March 8, 2007. (Inventors: R. Dave, R. Pfeffer, J. Yang, Y. Chen) (05-028; Application # 11/512,453, Patent - US 2007-0053846 A1)

  • Magnetically-Assisted Impact Mixing of Nanoparticle Systems, Provisional Patent Application filed, November 5, 2007. (Inventors: R. N. Dave, James Scicolone)

  • System and method for measuring or characterizing properties of ultra-fine or cohesive powders using vibrations, Provisional Patent Application filed, April 7, 2008, US Patent Application filed, US application # 12419792, April 7, 2009. (Inventors: R. N. Dave, Lauren Beach, M. Sanchez-Quintanilla)

  • Superdisintegrant-Based Nanocomposite Microparticles for Fast Redispersion and Dissolution of Active Pharmaceutical Agents, Provisional Patent Application filed, April 2012. Converted to non-provisional US Patent Application # 13/829,948, March 14, 2013. (Inventors: E. Bilgili, A. Bhakay, M. Azad, R. N. Davé)

  • Solventless Mixing Process for Coating Pharmaceutical Ingredients, Non-Provisional Patent Application, Application No. 13/651,977, filed, October 15, 2012, publication US-2014-0106059-A1, April 17, 2014. P.C.T. application number WO2013US64058 20131009, April 24, 2014, reference, WO2014062444 (A1) (Inventors: R. N. Davé, M. Capece, D. To)

  • A Process of Preparing Engineered Composite Particles and Applying a Bi‑Layer Coating by a Fluidized Bed Process, Non-Provisional Patent Application, Application No. 13/651,829, filed, October 15, 2012. (Inventors: R. N. Davé, D. To)

  • Pharmaceutical Core-Shell Composite Powder and Processes for Making the Same, Provisional Patent Application No. 61/725,301, filed, November 13, 2012; P.C.T. application WO2013US69128 20131108 filed, May 15, 2014, reference WO2014074808 (A1); international filings in process. (Inventors: R. N. Davé, C. Knieke, D. To, E. Bilgili, M. Azad)

  • Tablet coating via vibration induced mixing, Provisional Patent Application # 61/778,047, filed March 12, 2013. (Inventors: R. N. Davé, M. Capece)

  • System and method for fabrication of uniform polymer films containing nano and micro particles via continuous drying process, Provisional Patent Application # 61/791,752, filed March 15, 2013. International P.C.T. Application PCT/US2014/030506 filed, March 17, 2014. (Inventors: R. N. Davé, Ramani Susarla, Ecevit Bilgili, Boris Khusid, Fernando Muzzio, Lucas Sievens, Anagha Bhakay)

  • A method and system for incorporation and stabilization of proteins into polymer-based strip films and other forms for easy handling, dosing, storage, transport and recovery, Provisional Patent Application # 61/785,200, filed March 14, 2013. (Inventors: R. N. Davé, Ramani Susarla; Lizhong He and Zhangyang Zhao, Monash University)

  • Composites created by growing nanostructures directly onto a matrix material, US Patent Application # 14/169,395 Filed on 1/31/2014. (Inventors: Zafar Iqbal, Rajesn N. Dave, Rajen Patel and James Scicolone)

  • System and method for amorphous drug formulations with enhanced physical stability via dry polymer coating, Provisional Patent Application # 62/072,867 Filed on 10/30/2014. (Inventors: Maxx Capece and Rajesh Dave)

  • System and method for simultaneous dry polymer coating and milling of amorphous solids and amorphous dispersion drug formulations, Provisional Patent Application # 62/072,869 Filed on 10/30/2014. (Inventors: Maxx Capece and Rajesh Dave)

  • Taste masked active pharmaceutical powder compositions and processes for making them, P.C.T. application WO2013US64064 20131009, filed April 24, 2014, reference WO2014062446 (A1). (Inventors: D. To, R. N. Davé)

  • Dry processed surface engineered excipients, Provisional Patent Application # 62378384, Filed on 8/23/2016. (Inventors: Rajesh Dave) 

  • Dry processed surface engineered excipients, Non-Provisional Patent Application # 15684371, Filed 8/23/2017. (Inventors: Rajesh Dave, Liang Chen) 

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